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Enhanced anti‐angiogenic activity of novel melatonin‐like agents

Hypoxia‐inducible factor‐1 (HIF‐1) plays an important role in cellular responses to hypoxia, including the transcriptional activation of several genes involved in tumor angiogenesis. Melatonin, also known as N‐acetyl‐5‐methopxytryptamine, is produced naturally by the pineal gland and has anti‐angiog...

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Detalles Bibliográficos
Autores principales: Hwang, Su Jung, Jung, Yeonghun, Song, Ye‐Seul, Park, Suryeon, Park, Yohan, Lee, Hyo‐Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365647/
https://www.ncbi.nlm.nih.gov/pubmed/33955074
http://dx.doi.org/10.1111/jpi.12739