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Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture

Human induced pluripotent stem cells (hiPSCs) represent an unlimited cell source for the generation of patient-specific dopaminergic (DA) neurons, overcoming the hurdle of restricted accessibility to disease-affected tissue for mechanistic studies on Parkinson’s disease (PD). However, the complexity...

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Detalles Bibliográficos
Autores principales: Gilmozzi, Valentina, Gentile, Giovanna, Riekschnitz, Diana A., Von Troyer, Michael, Lavdas, Alexandros A., Kerschbamer, Emanuela, Weichenberger, Christian X., Rosato-Siri, Marcelo D., Casarosa, Simona, Conti, Luciano, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene, Zanon, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365765/
https://www.ncbi.nlm.nih.gov/pubmed/34409038
http://dx.doi.org/10.3389/fcell.2021.708389