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Generation of hiPSC-Derived Functional Dopaminergic Neurons in Alginate-Based 3D Culture
Human induced pluripotent stem cells (hiPSCs) represent an unlimited cell source for the generation of patient-specific dopaminergic (DA) neurons, overcoming the hurdle of restricted accessibility to disease-affected tissue for mechanistic studies on Parkinson’s disease (PD). However, the complexity...
Autores principales: | Gilmozzi, Valentina, Gentile, Giovanna, Riekschnitz, Diana A., Von Troyer, Michael, Lavdas, Alexandros A., Kerschbamer, Emanuela, Weichenberger, Christian X., Rosato-Siri, Marcelo D., Casarosa, Simona, Conti, Luciano, Pramstaller, Peter P., Hicks, Andrew A., Pichler, Irene, Zanon, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365765/ https://www.ncbi.nlm.nih.gov/pubmed/34409038 http://dx.doi.org/10.3389/fcell.2021.708389 |
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