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Protective effects of dexmedetomidine on cerebral ischemia/reperfusion injury via the microRNA-214/ROCK1/NF-κB axis

BACKGROUND: Cerebral ischemia/reperfusion injury (CIRI) is a complication of surgical procedure associated with high mortality. The protective effect of dexmedetomidine (DEX) on CIRI has been explored in previous works, yet the underlying molecular mechanism remains unclear. Our study explored the p...

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Detalles Bibliográficos
Autores principales: Liu, Wenyi, Shao, Cuihua, Zang, Chuanshan, Sun, Jian, Xu, Min, Wang, Yuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365892/
https://www.ncbi.nlm.nih.gov/pubmed/34399695
http://dx.doi.org/10.1186/s12871-021-01423-5