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Urinary metabolomic changes and microbiotic alterations in presenilin1/2 conditional double knockout mice
BACKGROUND: Given the clinical low efficient treatment based on mono-brain-target design in Alzheimer’s disease (AD) and an increasing emphasis on microbiome-gut-brain axis which was considered as a crucial pathway to affect the progress of AD along with metabolic changes, integrative metabolomic si...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365912/ https://www.ncbi.nlm.nih.gov/pubmed/34399766 http://dx.doi.org/10.1186/s12967-021-03032-9 |