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Urinary metabolomic changes and microbiotic alterations in presenilin1/2 conditional double knockout mice

BACKGROUND: Given the clinical low efficient treatment based on mono-brain-target design in Alzheimer’s disease (AD) and an increasing emphasis on microbiome-gut-brain axis which was considered as a crucial pathway to affect the progress of AD along with metabolic changes, integrative metabolomic si...

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Detalles Bibliográficos
Autores principales:	Gao, Jie, Zhou, Nian, Wu, Yongkang, Lu, Mengna, Wang, Qixue, Xia, Chenyi, Zhou, Mingmei, Xu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365912/ https://www.ncbi.nlm.nih.gov/pubmed/34399766 http://dx.doi.org/10.1186/s12967-021-03032-9

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