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Altered proTGFα/cleaved TGFα ratios offer new therapeutic strategies in renal carcinoma

BACKGROUND: Treatment of renal cancer has significantly improved with the arrival to the clinic of kinase inhibitors and immunotherapies. However, the disease is still incurable in advanced stages. The fact that several approved inhibitors for kidney cancer target receptor tyrosine kinases (RTKs) su...

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Detalles Bibliográficos
Autores principales: García-Alonso, Sara, Romero-Pérez, Inés, Gandullo-Sánchez, Lucía, Chinchilla, Luis, Ocaña, Alberto, Montero, Juan Carlos, Pandiella, Atanasio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365933/
https://www.ncbi.nlm.nih.gov/pubmed/34399807
http://dx.doi.org/10.1186/s13046-021-02051-0