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Nitric oxide-releasing micelles with intelligent targeting for enhanced anti-tumor effect of cisplatin in hypoxia

BACKGROUND: Hypoxic tumor microenvironment (TME) promotes tumor metastasis and drug resistance, leading to low efficiency of cancer chemotherapy. The development of targeted agents or multi-target therapies regulating hypoxic microenvironment is an important approach to overcome drug resistance and...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Fang, Lei, Zhou, Weixin, Chang, Jinghan, Zhang, Xiaojuan, He, Chuanchuan, Chen, Chen, Yan, Ruicong, Yan, Yakai, Lu, Yao, Xu, Chuanrui, Xiang, Guangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365946/
https://www.ncbi.nlm.nih.gov/pubmed/34399762
http://dx.doi.org/10.1186/s12951-021-00989-z