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Determination of myrislignan levels in BALB/c mouse plasma by LC-MS/MS and a comparison of its pharmacokinetics after oral and intraperitoneal administration

BACKGROUND: Myrislignan is a natural product from Myristica sp. with diverse pharmacological activities. Recently, the anti-Toxoplasma gondii (T. gondii) activity of myrislignan has been proposed, and in vivo studies of its pharmacokinetics in BALB/c mice are necessary to further evaluate the clinic...

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Detalles Bibliográficos
Autores principales: Zhang, Jili, Si, Hongfei, Sun, Jichao, Lv, Kun, Yan, Biqing, Li, Bing, Zhou, Xuzheng, Zhang, Jiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365968/
https://www.ncbi.nlm.nih.gov/pubmed/34399756
http://dx.doi.org/10.1186/s12917-021-02990-y