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Determination of myrislignan levels in BALB/c mouse plasma by LC-MS/MS and a comparison of its pharmacokinetics after oral and intraperitoneal administration
BACKGROUND: Myrislignan is a natural product from Myristica sp. with diverse pharmacological activities. Recently, the anti-Toxoplasma gondii (T. gondii) activity of myrislignan has been proposed, and in vivo studies of its pharmacokinetics in BALB/c mice are necessary to further evaluate the clinic...
Autores principales: | Zhang, Jili, Si, Hongfei, Sun, Jichao, Lv, Kun, Yan, Biqing, Li, Bing, Zhou, Xuzheng, Zhang, Jiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365968/ https://www.ncbi.nlm.nih.gov/pubmed/34399756 http://dx.doi.org/10.1186/s12917-021-02990-y |
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