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Mechanism of strand exchange from RecA-DNA synaptic and D-loop structures
The strand exchange reaction is central to homologous recombination. It is catalyzed by the RecA family of ATPases that form a helical filament with single-stranded DNA (ssDNA) and ATP. This filament binds to a donor double-stranded DNA (dsDNA) to form synaptic filaments that search for homology, an...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366275/ https://www.ncbi.nlm.nih.gov/pubmed/33057191 http://dx.doi.org/10.1038/s41586-020-2820-9 |