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Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma

Gankyrin is a regulatory subunit of the 26‐kD proteasome complex and promotes the occurrence and progression of many malignancies. However, the role of gankyrin in osteosarcoma (OS) metastasis remains unclear. Hedgehog signalling has been shown to regulate stem cell homeostasis and cancer metastasis...

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Detalles Bibliográficos
Autores principales: Wang, Chongchong, Jing, Juehua, Hu, Xuyang, Yu, Shuisheng, Yao, Fei, Li, Ziyu, Cheng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366451/
https://www.ncbi.nlm.nih.gov/pubmed/34089292
http://dx.doi.org/10.1111/jcmm.16576