Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell‐derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia syndrome that often leads to sudden cardiac death. The most common form of CPVT is caused by autosomal‐dominant variants in the cardiac ryanodine receptor type‐2 (RYR2) gene. Mutations in RYR2 promote cal...

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Detalles Bibliográficos
Autores principales: Word, Tarah A., Quick, Ann P., Miyake, Christina Y., Shak, Mayra K., Pan, Xiaolu, Kim, Jean J., Allen, Hugh D., Sibrian‐Vazquez, Martha, Strongin, Robert M., Landstrom, Andrew P., Wehrens, Xander H. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366453/
https://www.ncbi.nlm.nih.gov/pubmed/34110090
http://dx.doi.org/10.1111/jcmm.16521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366453/
https://www.ncbi.nlm.nih.gov/pubmed/34110090
http://dx.doi.org/10.1111/jcmm.16521

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