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Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell‐derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia syndrome that often leads to sudden cardiac death. The most common form of CPVT is caused by autosomal‐dominant variants in the cardiac ryanodine receptor type‐2 (RYR2) gene. Mutations in RYR2 promote cal...
Autores principales: | Word, Tarah A., Quick, Ann P., Miyake, Christina Y., Shak, Mayra K., Pan, Xiaolu, Kim, Jean J., Allen, Hugh D., Sibrian‐Vazquez, Martha, Strongin, Robert M., Landstrom, Andrew P., Wehrens, Xander H. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366453/ https://www.ncbi.nlm.nih.gov/pubmed/34110090 http://dx.doi.org/10.1111/jcmm.16521 |
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