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Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter

Th22 cells constitute a recently described CD4(+) T cell subset defined by its production of interleukin (IL)-22. The action of IL-22 is mainly restricted to epithelial cells. IL-22 enhances keratinocyte proliferation but inhibits their differentiation and maturation. Dysregulated IL-22 production h...

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Detalles Bibliográficos
Autores principales: Lopez, Daniel V., Al-Jaberi, Fatima A.H., Damas, Nkerorema D., Weinert, Brian T., Pus, Urska, Torres-Rusillo, Sara, Woetmann, Anders, Ødum, Niels, Bonefeld, Charlotte M., Kongsbak-Wismann, Martin, Geisler, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366496/
https://www.ncbi.nlm.nih.gov/pubmed/34408754
http://dx.doi.org/10.3389/fimmu.2021.715059