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Vitamin D Inhibits IL-22 Production Through a Repressive Vitamin D Response Element in the il22 Promoter
Th22 cells constitute a recently described CD4(+) T cell subset defined by its production of interleukin (IL)-22. The action of IL-22 is mainly restricted to epithelial cells. IL-22 enhances keratinocyte proliferation but inhibits their differentiation and maturation. Dysregulated IL-22 production h...
Autores principales: | Lopez, Daniel V., Al-Jaberi, Fatima A.H., Damas, Nkerorema D., Weinert, Brian T., Pus, Urska, Torres-Rusillo, Sara, Woetmann, Anders, Ødum, Niels, Bonefeld, Charlotte M., Kongsbak-Wismann, Martin, Geisler, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366496/ https://www.ncbi.nlm.nih.gov/pubmed/34408754 http://dx.doi.org/10.3389/fimmu.2021.715059 |
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