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Antitumor activity of the third generation EphA2 CAR-T cells against glioblastoma is associated with interferon gamma induced PD-L1

Glioblastoma (GBM) is the most common and aggressive brain malignancy in adults and is currently incurable with conventional therapies. The use of chimeric antigen receptor (CAR) modified T cells has been successful in clinical treatment of blood cancers, except solid tumors such as GBM. This study...

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Detalles Bibliográficos
Autores principales: an, Zhijing, Hu, Yi, Bai, Yue, Zhang, Can, Xu, Chang, Kang, Xun, Yang, Shoubo, Li, Wenbin, Zhong, Xiaosong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366541/
https://www.ncbi.nlm.nih.gov/pubmed/34408922
http://dx.doi.org/10.1080/2162402X.2021.1960728