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An Overview of Investigational and Experimental Drug Treatment Strategies for Marfan Syndrome

Marfan syndrome (MFS) is a heritable connective tissue disorder caused by pathogenic variants in the gene coding for the extracellular matrix protein fibrillin-1. While the disease affects multiple organ systems, the most life-threatening manifestations are aortic aneurysms leading to dissection and...

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Detalles Bibliográficos
Autores principales: Deleeuw, Violette, De Clercq, Adelbert, De Backer, Julie, Sips, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366784/
https://www.ncbi.nlm.nih.gov/pubmed/34408505
http://dx.doi.org/10.2147/JEP.S265271