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A novel heteromeric pantothenate kinase complex in apicomplexan parasites

Coenzyme A is synthesised from pantothenate via five enzyme-mediated steps. The first step is catalysed by pantothenate kinase (PanK). All PanKs characterised to date form homodimers. Many organisms express multiple PanKs. In some cases, these PanKs are not functionally redundant, and some appear to...

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Detalles Bibliográficos
Autores principales: Tjhin, Erick T., Howieson, Vanessa M., Spry, Christina, van Dooren, Giel G., Saliba, Kevin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366970/
https://www.ncbi.nlm.nih.gov/pubmed/34324601
http://dx.doi.org/10.1371/journal.ppat.1009797