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A novel heteromeric pantothenate kinase complex in apicomplexan parasites
Coenzyme A is synthesised from pantothenate via five enzyme-mediated steps. The first step is catalysed by pantothenate kinase (PanK). All PanKs characterised to date form homodimers. Many organisms express multiple PanKs. In some cases, these PanKs are not functionally redundant, and some appear to...
Autores principales: | Tjhin, Erick T., Howieson, Vanessa M., Spry, Christina, van Dooren, Giel G., Saliba, Kevin J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8366970/ https://www.ncbi.nlm.nih.gov/pubmed/34324601 http://dx.doi.org/10.1371/journal.ppat.1009797 |
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