Discovery and validation of a three-gene signature to distinguish COVID-19 and other viral infections in emergency infectious disease presentations: a case-control and observational cohort study

BACKGROUND: Emergency admissions for infection often lack initial diagnostic certainty. COVID-19 has highlighted a need for novel diagnostic approaches to indicate likelihood of viral infection in a pandemic setting. We aimed to derive and validate a blood transcriptional signature to detect viral i...

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Detalles Bibliográficos
Autores principales: Li, Ho Kwong, Kaforou, Myrsini, Rodriguez-Manzano, Jesus, Channon-Wells, Samuel, Moniri, Ahmad, Habgood-Coote, Dominic, Gupta, Rishi K, Mills, Ewurabena A, Arancon, Dominique, Lin, Jessica, Chiu, Yueh-Ho, Pennisi, Ivana, Miglietta, Luca, Mehta, Ravi, Obaray, Nelofar, Herberg, Jethro A, Wright, Victoria J, Georgiou, Pantelis, Shallcross, Laura J, Mentzer, Alexander J, Levin, Michael, Cooke, Graham S, Noursadeghi, Mahdad, Sriskandan, Shiranee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367196/
https://www.ncbi.nlm.nih.gov/pubmed/34423323
http://dx.doi.org/10.1016/S2666-5247(21)00145-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367196/
https://www.ncbi.nlm.nih.gov/pubmed/34423323
http://dx.doi.org/10.1016/S2666-5247(21)00145-2

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