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Discovery and validation of a three-gene signature to distinguish COVID-19 and other viral infections in emergency infectious disease presentations: a case-control and observational cohort study
BACKGROUND: Emergency admissions for infection often lack initial diagnostic certainty. COVID-19 has highlighted a need for novel diagnostic approaches to indicate likelihood of viral infection in a pandemic setting. We aimed to derive and validate a blood transcriptional signature to detect viral i...
Autores principales: | Li, Ho Kwong, Kaforou, Myrsini, Rodriguez-Manzano, Jesus, Channon-Wells, Samuel, Moniri, Ahmad, Habgood-Coote, Dominic, Gupta, Rishi K, Mills, Ewurabena A, Arancon, Dominique, Lin, Jessica, Chiu, Yueh-Ho, Pennisi, Ivana, Miglietta, Luca, Mehta, Ravi, Obaray, Nelofar, Herberg, Jethro A, Wright, Victoria J, Georgiou, Pantelis, Shallcross, Laura J, Mentzer, Alexander J, Levin, Michael, Cooke, Graham S, Noursadeghi, Mahdad, Sriskandan, Shiranee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367196/ https://www.ncbi.nlm.nih.gov/pubmed/34423323 http://dx.doi.org/10.1016/S2666-5247(21)00145-2 |
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