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CLAMP and Zelda function together to promote Drosophila zygotic genome activation

During the essential and conserved process of zygotic genome activation (ZGA), chromatin accessibility must increase to promote transcription. Drosophila is a well-established model for defining mechanisms that drive ZGA. Zelda (ZLD) is a key pioneer transcription factor (TF) that promotes ZGA in th...

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Detalles Bibliográficos
Autores principales: Duan, Jingyue, Rieder, Leila, Colonnetta, Megan M, Huang, Annie, Mckenney, Mary, Watters, Scott, Deshpande, Girish, Jordan, William, Fawzi, Nicolas, Larschan, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367384/
https://www.ncbi.nlm.nih.gov/pubmed/34342574
http://dx.doi.org/10.7554/eLife.69937