Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes

Drug-induced cardiotoxicity and hepatotoxicity are major causes of drug attrition. To decrease late-stage drug attrition, pharmaceutical and biotechnology industries need to establish biologically relevant models that use phenotypic screening to detect drug-induced toxicity in vitro. In this study,...

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Detalles Bibliográficos
Autores principales: Grafton, Francis, Ho, Jaclyn, Ranjbarvaziri, Sara, Farshidfar, Farshad, Budan, Anastasiia, Steltzer, Stephanie, Maddah, Mahnaz, Loewke, Kevin E, Green, Kristina, Patel, Snahel, Hoey, Tim, Mandegar, Mohammad Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367386/
https://www.ncbi.nlm.nih.gov/pubmed/34338636
http://dx.doi.org/10.7554/eLife.68714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367386/
https://www.ncbi.nlm.nih.gov/pubmed/34338636
http://dx.doi.org/10.7554/eLife.68714

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