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Deep learning detects cardiotoxicity in a high-content screen with induced pluripotent stem cell-derived cardiomyocytes
Drug-induced cardiotoxicity and hepatotoxicity are major causes of drug attrition. To decrease late-stage drug attrition, pharmaceutical and biotechnology industries need to establish biologically relevant models that use phenotypic screening to detect drug-induced toxicity in vitro. In this study,...
Autores principales: | Grafton, Francis, Ho, Jaclyn, Ranjbarvaziri, Sara, Farshidfar, Farshad, Budan, Anastasiia, Steltzer, Stephanie, Maddah, Mahnaz, Loewke, Kevin E, Green, Kristina, Patel, Snahel, Hoey, Tim, Mandegar, Mohammad Ali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367386/ https://www.ncbi.nlm.nih.gov/pubmed/34338636 http://dx.doi.org/10.7554/eLife.68714 |
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