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miR-223 Inhibits the Polarization and Recruitment of Macrophages via NLRP3/IL-1β Pathway to Meliorate Neuropathic Pain

BACKGROUND: miRNA is an essential factor in neuropathic pain. However, the underlying mechanism of miRNA in neuropathic pain remains unclear. OBJECTIVE: To explore the potential role of miR-223 in neuropathic pain in a mice model of chronic sciatic nerve injury. METHODS: Mice were divided into the s...

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Detalles Bibliográficos
Autores principales: Zhu, Junsong, Yang, Jinmei, Xu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367593/
https://www.ncbi.nlm.nih.gov/pubmed/34408803
http://dx.doi.org/10.1155/2021/6674028