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Structural deformability induced in proteins of potential interest associated with COVID-19 by binding of homologues present in ivermectin: Comparative study based in elastic networks models

The COVID-19 pandemic has accelerated the study of the potential of multi-target drugs (MTDs). The mixture of homologues called ivermectin (avermectin-B1a + avermectin-B1b) has been shown to be a MTD with potential antiviral activity against SARS-CoV-2 in vitro. However, there are few reports on the...

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Detalles Bibliográficos
Autores principales: González-Paz, Lenin, Hurtado-León, María Laura, Lossada, Carla, Fernández-Materán, Francelys V., Vera-Villalobos, Joan, Loroño, Marcos, Paz, J.L., Jeffreys, Laura, Alvarado, Ysaias J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367659/
https://www.ncbi.nlm.nih.gov/pubmed/34421159
http://dx.doi.org/10.1016/j.molliq.2021.117284