Pretreatment with valproic acid alleviates pulmonary fibrosis through epithelial–mesenchymal transition inhibition in vitro and in vivo

Epithelial–mesenchymal transition (EMT) plays a crucial role in the development of pulmonary fibrosis. This study aims to investigate the effects of valproic acid (VPA) on EMT in vitro and in vivo. In vitro, EMT was induced by the administration of transforming growth factor-β1 (TGF-β1) in a human a...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Lin, Alam, Azeem, Pac-Soo, Aurelie, Chen, Qian, Shang, You, Zhao, Hailin, Yao, Shanglong, Ma, Daqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367813/
https://www.ncbi.nlm.nih.gov/pubmed/34168289
http://dx.doi.org/10.1038/s41374-021-00617-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367813/
https://www.ncbi.nlm.nih.gov/pubmed/34168289
http://dx.doi.org/10.1038/s41374-021-00617-2

Ejemplares similares