Hesperetin inhibits foam cell formation and promotes cholesterol efflux in THP-1-derived macrophages by activating LXRα signal in an AMPK-dependent manner

Cholesterol efflux from macrophages is the first step of reverse cholesterol transport (RCT), whose increase inhibits cholesterol accumulation and foam cell formation to suppress atherogenesis. Hesperetin has been reported to exert several protective effects on cardiovascular diseases, while little...

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Detalles Bibliográficos
Autores principales: Chen, Xuanjing, Zou, Dezhi, Chen, Xiaoling, Wu, Huanlin, Xu, Danping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367930/
https://www.ncbi.nlm.nih.gov/pubmed/34212313
http://dx.doi.org/10.1007/s13105-020-00783-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367930/
https://www.ncbi.nlm.nih.gov/pubmed/34212313
http://dx.doi.org/10.1007/s13105-020-00783-9

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