Cargando…

Chimeric virus-like particles (VLPs) designed from shrimp nodavirus (MrNV) capsid protein specifically target EGFR-positive human colorectal cancer cells

Recombinant MrNV capsid protein has been shown to effectively deliver plasmid DNA and dsRNA into Sf9 insect cells and shrimp tissues. To extend its application to cancer cell-targeting drug delivery, we created three different types of chimeric MrNV virus-like particles (VLPs) (R-MrNV, I-MrNV, and E...

Descripción completa

Detalles Bibliográficos
Autores principales: Grataitong, Khwanthana, Huault, Sébastien, Chotwiwatthanakun, Charoonroj, Jariyapong, Pitchanee, Thongsum, Orawan, Chawiwithaya, Chidchanok, Chakrabandhu, Krittalak, Hueber, Anne-Odile, Weerachatyanukul, Wattana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367941/
https://www.ncbi.nlm.nih.gov/pubmed/34400669
http://dx.doi.org/10.1038/s41598-021-95891-x