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Chimeric virus-like particles (VLPs) designed from shrimp nodavirus (MrNV) capsid protein specifically target EGFR-positive human colorectal cancer cells
Recombinant MrNV capsid protein has been shown to effectively deliver plasmid DNA and dsRNA into Sf9 insect cells and shrimp tissues. To extend its application to cancer cell-targeting drug delivery, we created three different types of chimeric MrNV virus-like particles (VLPs) (R-MrNV, I-MrNV, and E...
Autores principales: | Grataitong, Khwanthana, Huault, Sébastien, Chotwiwatthanakun, Charoonroj, Jariyapong, Pitchanee, Thongsum, Orawan, Chawiwithaya, Chidchanok, Chakrabandhu, Krittalak, Hueber, Anne-Odile, Weerachatyanukul, Wattana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367941/ https://www.ncbi.nlm.nih.gov/pubmed/34400669 http://dx.doi.org/10.1038/s41598-021-95891-x |
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