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LineageOT is a unified framework for lineage tracing and trajectory inference

Understanding the genetic and epigenetic programs that control differentiation during development is a fundamental challenge, with broad impacts across biology and medicine. Measurement technologies like single-cell RNA-sequencing and CRISPR-based lineage tracing have opened new windows on these pro...

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Detalles Bibliográficos
Autores principales: Forrow, Aden, Schiebinger, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367995/
https://www.ncbi.nlm.nih.gov/pubmed/34400634
http://dx.doi.org/10.1038/s41467-021-25133-1