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How the glucocorticoid receptor contributes to platinum-based therapy resistance in solid cancer

Synthetic glucocorticoids serve as co-medication against solid malignant tumors. However, glucocorticoid receptor activation may promote unsolicited cancer resistance to chemotherapy. The Kang team elucidated a glucocorticoid receptor-centred chemotherapy-resistance mechanism to cisplatin and charac...

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Detalles Bibliográficos
Autores principales: Clarisse, Dorien, De Bosscher, Karolien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8367998/
https://www.ncbi.nlm.nih.gov/pubmed/34400619
http://dx.doi.org/10.1038/s41467-021-24847-6