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Cisplatin-mediated activation of glucocorticoid receptor induces platinum resistance via MAST1

Agonists of glucocorticoid receptor (GR) are frequently given to cancer patients with platinum-containing chemotherapy to reduce inflammation, but how GR influences tumor growth in response to platinum-based chemotherapy such as cisplatin through inflammation-independent signaling remains largely un...

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Detalles Bibliográficos
Autores principales: Pan, Chaoyun, Kang, JiHoon, Hwang, Jung Seok, Li, Jie, Boese, Austin C., Wang, Xu, Yang, Likun, Boggon, Titus J., Chen, Georgia Z., Saba, Nabil F., Shin, Dong M., Magliocca, Kelly R., Jin, Lingtao, Kang, Sumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368102/
https://www.ncbi.nlm.nih.gov/pubmed/34400618
http://dx.doi.org/10.1038/s41467-021-24845-8