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Offspring born to influenza A virus infected pregnant mice have increased susceptibility to viral and bacterial infections in early life

Influenza during pregnancy can affect the health of offspring in later life, among which neurocognitive disorders are among the best described. Here, we investigate whether maternal influenza infection has adverse effects on immune responses in offspring. We establish a two-hit mouse model to study...

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Detalles Bibliográficos
Autores principales: Jacobsen, Henning, Walendy-Gnirß, Kerstin, Tekin-Bubenheim, Nilgün, Kouassi, Nancy Mounogou, Ben-Batalla, Isabel, Berenbrok, Nikolaus, Wolff, Martin, dos Reis, Vinicius Pinho, Zickler, Martin, Scholl, Lucas, Gries, Annette, Jania, Hanna, Kloetgen, Andreas, Düsedau, Arne, Pilnitz-Stolze, Gundula, Jeridi, Aicha, Yildirim, Ali Önder, Fuchs, Helmut, Gailus-Durner, Valerie, Stoeger, Claudia, de Angelis, Martin Hrabe, Manuylova, Tatjana, Klingel, Karin, Culley, Fiona J., Behrends, Jochen, Loges, Sonja, Schneider, Bianca, Krauss-Etschmann, Susanne, Openshaw, Peter, Gabriel, Gülsah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368105/
https://www.ncbi.nlm.nih.gov/pubmed/34400653
http://dx.doi.org/10.1038/s41467-021-25220-3