Understanding Intra-Species and Inter-Species Prion Conversion and Zoonotic Potential Using Protein Misfolding Cyclic Amplification

Prion diseases are fatal neurodegenerative disorders that affect humans and animals, and can also be transmitted from animals to humans. A fundamental event in prion disease pathogenesis is the conversion of normal host prion protein (PrP(C)) to a disease-associated misfolded form (PrP(Sc)). Whether...

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Detalles Bibliográficos
Autores principales: Peden, Alexander H., Suleiman, Suzanne, Barria, Marcelo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368127/
https://www.ncbi.nlm.nih.gov/pubmed/34413769
http://dx.doi.org/10.3389/fnagi.2021.716452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368127/
https://www.ncbi.nlm.nih.gov/pubmed/34413769
http://dx.doi.org/10.3389/fnagi.2021.716452

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