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Understanding Intra-Species and Inter-Species Prion Conversion and Zoonotic Potential Using Protein Misfolding Cyclic Amplification
Prion diseases are fatal neurodegenerative disorders that affect humans and animals, and can also be transmitted from animals to humans. A fundamental event in prion disease pathogenesis is the conversion of normal host prion protein (PrP(C)) to a disease-associated misfolded form (PrP(Sc)). Whether...
Autores principales: | Peden, Alexander H., Suleiman, Suzanne, Barria, Marcelo A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368127/ https://www.ncbi.nlm.nih.gov/pubmed/34413769 http://dx.doi.org/10.3389/fnagi.2021.716452 |
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