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Cardioprotective effects of early intervention with sacubitril/valsartan on pressure overloaded rat hearts

Left ventricular remodeling due to pressure overload is associated with poor prognosis. Sacubitril/valsartan is the first-in-class Angiotensin Receptor Neprilysin Inhibitor and has been demonstrated to have superior beneficial effects in the settings of heart failure. The aim of this study was to de...

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Detalles Bibliográficos
Autores principales: Li, Xiaofei, Braza, Julie, Mende, Ulrike, Choudhary, Gaurav, Zhang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368201/
https://www.ncbi.nlm.nih.gov/pubmed/34400686
http://dx.doi.org/10.1038/s41598-021-95988-3