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Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection

We have shown that calcium-activated potassium (KCa)-channels regulate fundamental progenitor-cell functions, including proliferation, but their contribution to cell-therapy effectiveness is unknown. Here, we test the participation of KCa-channels in human heart explant-derived cell (EDC) physiology...

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Detalles Bibliográficos
Autores principales: Vigneault, Patrick, Parent, Sandrine, Kanda, Pushpinder, Michie, Connor, Davis, Darryl R., Nattel, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368210/
https://www.ncbi.nlm.nih.gov/pubmed/34400625
http://dx.doi.org/10.1038/s41467-021-25180-8