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Electrophysiological engineering of heart-derived cells with calcium-dependent potassium channels improves cell therapy efficacy for cardioprotection
We have shown that calcium-activated potassium (KCa)-channels regulate fundamental progenitor-cell functions, including proliferation, but their contribution to cell-therapy effectiveness is unknown. Here, we test the participation of KCa-channels in human heart explant-derived cell (EDC) physiology...
Autores principales: | Vigneault, Patrick, Parent, Sandrine, Kanda, Pushpinder, Michie, Connor, Davis, Darryl R., Nattel, Stanley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368210/ https://www.ncbi.nlm.nih.gov/pubmed/34400625 http://dx.doi.org/10.1038/s41467-021-25180-8 |
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