Cargando…

The Transcriptomic Profile of Monocytes from Patients With Sjögren’s Syndrome Is Associated With Inflammatory Parameters and Is Mimicked by Circulating Mediators

Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease characterized by infiltration of the exocrine glands and prominent B cell hyperactivity. Considering the key role of monocytes in promoting B cell hyperactivity, we performed RNA-sequencing analysis of CD14(+) monocytes from patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Lopes, Ana P., Bekker, Cornelis P. J., Hillen, Maarten R., Blokland, Sofie L. M., Hinrichs, Anneline C., Pandit, Aridaman, Kruize, Aike A., Radstake, Timothy R. D. J., van Roon, Joel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368727/
https://www.ncbi.nlm.nih.gov/pubmed/34413853
http://dx.doi.org/10.3389/fimmu.2021.701656