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ceRNA regulatory network of FIH inhibitor as a radioprotector for gastrointestinal toxicity by activating the HIF-1 pathway

Given the relentless renewal ability of intestinal crypt-base stem cells, small intestine in the gastrointestinal (GI) tract is more vulnerable to radiation-induced disruption. Through promoting epithelial integrity and reducing intracellular reactive oxygen species (ROS) levels, hypoxia-inducible f...

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Detalles Bibliográficos
Autores principales: Yang, Yu-wei, Meng, Xin, Meng, Yuan-yuan, Tang, Hai-kang, Cheng, Ming-hui, Zhang, Zi-qi, Xu, Wen-qing, Long, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368776/
https://www.ncbi.nlm.nih.gov/pubmed/34458003
http://dx.doi.org/10.1016/j.omtn.2021.05.008