Cargando…

ceRNA regulatory network of FIH inhibitor as a radioprotector for gastrointestinal toxicity by activating the HIF-1 pathway

Given the relentless renewal ability of intestinal crypt-base stem cells, small intestine in the gastrointestinal (GI) tract is more vulnerable to radiation-induced disruption. Through promoting epithelial integrity and reducing intracellular reactive oxygen species (ROS) levels, hypoxia-inducible f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Yu-wei, Meng, Xin, Meng, Yuan-yuan, Tang, Hai-kang, Cheng, Ming-hui, Zhang, Zi-qi, Xu, Wen-qing, Long, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368776/ https://www.ncbi.nlm.nih.gov/pubmed/34458003 http://dx.doi.org/10.1016/j.omtn.2021.05.008

Ejemplares similares

Factor-inhibiting HIF (FIH) promotes lung cancer progression
por: García-del Río, Ana, et al.
Publicado: (2023)

Construction of ceRNA regulatory networks for osteoporosis
por: Chen, Hongtao, et al.
Publicado: (2023)

Radioprotectors.org: an open database of known and predicted radioprotectors
por: Aliper, Alexander M., et al.
Publicado: (2020)

Identification of CeRNA Regulatory Networks in Atrial Fibrillation Using Nanodelivery
por: Lin, Ping, et al.
Publicado: (2022)

The Role of Factor Inhibiting HIF (FIH-1) in Inhibiting HIF-1 Transcriptional Activity in Glioblastoma Multiforme
por: Wang, Enfeng, et al.
Publicado: (2014)

The FIH hydroxylase is a cellular peroxide sensor that modulates HIF transcriptional activity
por: Masson, Norma, et al.
Publicado: (2012)

Construction and dissection of the ceRNA-ceRNA network reveals critical modules in depression
por: Lang, Yan, et al.
Publicado: (2019)

Pharmacology of natural radioprotectors
por: Mun, Gil-Im, et al.
Publicado: (2018)

ce‐Subpathway: Identification of ceRNA‐mediated subpathways via joint power of ceRNAs and pathway topologies
por: Feng, Chenchen, et al.
Publicado: (2018)

Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectively
por: Wang, Yihua, et al.
Publicado: (2018)

The conservation and functionality of the oxygen-sensing enzyme Factor Inhibiting HIF (FIH) in non-vertebrates
por: Hampton-Smith, Rachel J., et al.
Publicado: (2019)

Interactions between Distant ceRNAs in Regulatory Networks
por: Nitzan, Mor, et al.
Publicado: (2014)

High-throughput validation of ceRNA regulatory networks
por: Chiu, Hua-Sheng, et al.
Publicado: (2017)

IMF deposition ceRNA network analysis and functional study of HIF1a in yak
por: Luo, Mengning, et al.
Publicado: (2023)

Correction to: Pharmacology of natural radioprotectors
por: Mun, Gil-Im, et al.
Publicado: (2019)

Correction to: Pharmacology of natural radioprotectors
por: Mun, Gil-Im, et al.
Publicado: (2019)

FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α
por: Kang, Jengmin, et al.
Publicado: (2018)

Comprehensive analysis of differentially expressed circRNAs and ceRNA regulatory network in porcine skeletal muscle
por: Li, Meng, et al.
Publicado: (2021)

Prognostic Roles of ceRNA Network-Based Signatures in Gastrointestinal Cancers
por: Qi, Xin, et al.
Publicado: (2022)

Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
por: Hyseni, Agon, et al.
Publicado: (2011)

Autophagy Induced by BCL2-Related ceRNA Network Participates in the Occurrence of COPD
por: Shi, Zhuang-E, et al.
Publicado: (2022)

miRTissue (ce): extending miRTissue web service with the analysis of ceRNA-ceRNA interactions
por: Fiannaca, Antonino, et al.
Publicado: (2020)

ceRNAs in Cancer: Mechanism and Functions in a Comprehensive Regulatory Network
por: Yang, Ni, et al.
Publicado: (2021)

The regulatory mechanism of LncRNA-mediated ceRNA network in osteosarcoma
por: Lin, Chengsen, et al.
Publicado: (2022)

Research progress on the circRNA-mediated regulation of tumor angiogenesis through ceRNA mechanisms
por: Meng, Dandan, et al.
Publicado: (2022)

Construction and Comparison of ceRNA Regulatory Network for Different Age Female Breast Cancer
por: Liu, Zhi-Qin, et al.
Publicado: (2021)

Construction and Investigation of a lncRNA-Associated ceRNA Regulatory Network in Cholangiocarcinoma
por: Long, Junyu, et al.
Publicado: (2019)

The hsa_circ_0000276-ceRNA regulatory network and immune infiltration in cervical cancer
por: Zhang, Honglei, et al.
Publicado: (2023)

Study on the Relationship between the miRNA-centered ceRNA Regulatory Network and Fatigue
por: Yang, Xingzhe, et al.
Publicado: (2021)

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis
por: Khan, M N, et al.
Publicado: (2011)

Construction of a Diagnostic Model and a lncRNA-Associated ceRNA Network Based on Apoptosis-Related Genes for Schizophrenia
por: Ma, Zi-long, et al.
Publicado: (2023)

The Functional Characterization of Epigenetically Related lncRNAs Involved in Dysregulated CeRNA–CeRNA Networks Across Eight Cancer Types
por: Xu, Dahua, et al.
Publicado: (2021)

A ceRNA regulatory network in systemic lupus erythematosus and its molecular interplay with cancer
por: Lin, Shunsheng, et al.
Publicado: (2022)

Construction of ceRNA Networks at Different Stages of Somatic Embryogenesis in Garlic
por: Bai, Yunhe, et al.
Publicado: (2023)

Natural radioprotectors and their impact on cancer drug discovery
por: Kuruba, Vinutha, et al.
Publicado: (2018)

Use of Ganoderma lucidum (Ganodermataceae, Basidiomycota) as Radioprotector
por: González, Aránzazu, et al.
Publicado: (2020)

Extensive ceRNA–ceRNA interaction networks mediated by miRNAs regulate development in multiple rhesus tissues
por: Xu, Juan, et al.
Publicado: (2016)

Identification of biomarkers and pathways in hypertensive nephropathy based on the ceRNA regulatory network
por: Wang, Zhen, et al.
Publicado: (2020)

To construct a ceRNA regulatory network as prognostic biomarkers for bladder cancer
por: Jiang, Jiazhi, et al.
Publicado: (2020)

The role of lncRNA-mediated ceRNA regulatory networks in pancreatic cancer
por: Xu, Jichuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qrrprq4q0vjou315it68ru0b7a