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Protective effect of LNA-anti-miR-132 therapy on liver fibrosis in mice

microRNAs (miRs) are small regulatory RNAs that are frequently deregulated in liver disease. Liver fibrosis is characterized by excessive scarring caused by chronic inflammatory processes. In this study, we determined the functional role of miR-132 using a locked nucleic acid (LNA)-anti-miR approach...

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Detalles Bibliográficos
Autores principales: Momen-Heravi, Fatemeh, Catalano, Donna, Talis, Austin, Szabo, Gyongyi, Bala, Shashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368790/
https://www.ncbi.nlm.nih.gov/pubmed/34458001
http://dx.doi.org/10.1016/j.omtn.2021.05.007