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Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission

The capacity of the brain to elicit sustained remission of hyperglycemia in rodent models of type 2 diabetes following intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) is well established. Here, we show that following icv FGF1 injection, hypothalamic signaling by extracel...

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Detalles Bibliográficos
Autores principales: Brown, Jenny M., Bentsen, Marie A., Rausch, Dylan M., Phan, Bao Anh, Wieck, Danielle, Wasanwala, Huzaifa, Matsen, Miles E., Acharya, Nikhil, Richardson, Nicole E., Zhao, Xin, Zhai, Peng, Secher, Anna, Morton, Gregory J., Pers, Tune H., Schwartz, Michael W., Scarlett, Jarrad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368994/
https://www.ncbi.nlm.nih.gov/pubmed/34430821
http://dx.doi.org/10.1016/j.isci.2021.102944