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Role of hypothalamic MAPK/ERK signaling and central action of FGF1 in diabetes remission
The capacity of the brain to elicit sustained remission of hyperglycemia in rodent models of type 2 diabetes following intracerebroventricular (icv) injection of fibroblast growth factor 1 (FGF1) is well established. Here, we show that following icv FGF1 injection, hypothalamic signaling by extracel...
Autores principales: | Brown, Jenny M., Bentsen, Marie A., Rausch, Dylan M., Phan, Bao Anh, Wieck, Danielle, Wasanwala, Huzaifa, Matsen, Miles E., Acharya, Nikhil, Richardson, Nicole E., Zhao, Xin, Zhai, Peng, Secher, Anna, Morton, Gregory J., Pers, Tune H., Schwartz, Michael W., Scarlett, Jarrad M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368994/ https://www.ncbi.nlm.nih.gov/pubmed/34430821 http://dx.doi.org/10.1016/j.isci.2021.102944 |
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