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Basic residues at the C-gate of DNA gyrase are involved in DNA supercoiling

DNA gyrase is a type II topoisomerase that is responsible for maintaining the topological state of bacterial and some archaeal genomes. It uses an ATP-dependent two-gate strand-passage mechanism that is shared among all type II topoisomerases. During this process, DNA gyrase creates a transient brea...

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Detalles Bibliográficos
Autores principales: Smith, Eric M., Mondragón, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8368997/
https://www.ncbi.nlm.nih.gov/pubmed/34303706
http://dx.doi.org/10.1016/j.jbc.2021.101000