BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology

Alzheimer’s disease (AD) is the most common progressive neurodegenerative disease. However, the underlying molecular mechanism is incompletely understood. Here we report that the pro-apoptotic protein BAD as a key regulator for neuronal apoptosis, neuroinflammation and Aβ clearance in AD. BAD pro-ap...

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Detalles Bibliográficos
Autores principales: Zhang, Liansheng, Qian, Yun, Li, Jie, Zhou, Xuan, Xu, He, Yan, Jie, Xiang, Jialing, Yuan, Xiang, Sun, Beicheng, Sisodia, Sangram S., Jiang, Yong-Hui, Cao, Xiaohua, Jing, Naihe, Lin, Anning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
https://www.ncbi.nlm.nih.gov/pubmed/34430820
http://dx.doi.org/10.1016/j.isci.2021.102942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369003/
https://www.ncbi.nlm.nih.gov/pubmed/34430820
http://dx.doi.org/10.1016/j.isci.2021.102942

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