Atomic-Level Investigation of Reactant Recognition Mechanism and Thermodynamic Property in Glucosamine 6-Phosphate Deaminase Catalysis

Glucosamine 6-phosphate deaminase (NagB) influences the direction of N-acetylglucosamine (GlcNAc) metabolism, facilitating the conversion of D-glucosamine 6-phosphate (GlcN6P) to D-fructose 6-phosphate (Fru6P) with the release of ammonia. Here, extensive molecular dynamics simulations combined with...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Liu, Xiaoyuan, Zhang, Zhiyang, Zhao, Yuan, Wang, Chaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369159/
https://www.ncbi.nlm.nih.gov/pubmed/34414167
http://dx.doi.org/10.3389/fchem.2021.737492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369159/
https://www.ncbi.nlm.nih.gov/pubmed/34414167
http://dx.doi.org/10.3389/fchem.2021.737492

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