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Interpretable systems biomarkers predict response to immune-checkpoint inhibitors
Cancer cells can leverage several cell-intrinsic and -extrinsic mechanisms to escape immune system recognition. The inherent complexity of the tumor microenvironment, with its multicellular and dynamic nature, poses great challenges for the extraction of biomarkers of immune response and immunothera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369166/ https://www.ncbi.nlm.nih.gov/pubmed/34430923 http://dx.doi.org/10.1016/j.patter.2021.100293 |